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Product name: Selumetinib
Other name: 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide; 6-(4-bromo-2-chlorophenylamino)-7-fluoro-N-(2-hydroxyethoxy)-3-methyl-3H-benzo[d]imidazole-5-carboxamide; Selumetinib; AZD6244; 5-[ (4-BROMO-2-CHLOROPHENYL)AMINO]-4-FLUORO-N-(2-HYDROXYETHOXY)-1-METHYL-1H-BENZIMIDAZOLE-6-CARBOXAMIDE;
MF:C17H15BrClFN4O3
MW:457.685
CAS:606143-52-6
Appearance and traits: white or light white solid
Density: 1.69
Storage conditions: Powder stores in -20oC directly, which is effective for a period of 2 years.
Customs Code: 2934999090
Package: 100g/foil bag
Smetatinib Description
Smetatinib, in previous studies, showed that sematantin also has the effect of treating metastatic biliary cancer.
The first-line treatment strategy for low-grade serous ovarian cancer is surgery followed by radiotherapy. However, this type of tumor grows slowly and responds poorly to traditional chemotherapy drugs. Because MEK gene mutations have been demonstrated in low-grade serous ovarian or peritoneal cancers, studies using MEK-1/2 protein kinases targeting mitogen-activated protein kinase (MAPK) pathway have been performed with seletinib. The study was performed on 52 patients with 100 mg of seletinib administered orally twice a day for 4 weeks, and 33% of patients received 12 or more cycles of treatment. Before the start of the study, 58% of patients had received 3 or more cycles of chemotherapy. Simetinib controlled disease in 81% of patients. In particular, 8 patients had complete or partial remission, and 34 had stable disease. The median progression-free survival was 11 months, and 63% of patients had a progression-free survival of more than 6 months. In addition, patients were well tolerated with simetinib and only 3 patients experienced grade 4 adverse events.
The clinical application of MEK inhibitors (mitogen activation inhibitors) is gradually being applied. It can be used first to treat chronic pain, inhibit cancer cell proliferation, treat non-small cell lung cancer, and MEK inhibitors can be combined with nilotinib to overcome them. Chronic myelogenous leukemia (CML) resistance. Recent treatment of metastatic biliary cancer and control of low-grade serous ovarian or peritoneal cancer. Therefore, the MEK inhibitor seletinib will become a new drug for treating cancer.
Factory and workshop
 Commerce Clause
Minimum Order Quantity:
100gram
Price:
Negotiable
Payment Terms:
Western Union, MoneyGram, T/T, Bank Transfer;Bitcoin
Packaging Details:
Discreet and Disguised packing
Delivery time:
Within 12 hours after receiving the payment
Leading time:
4~6 working days after confirming the payment
Delivery
By DHL, TNT, FedEx, HKEMS, UPS, etc.(Door to Door)bulk order can be negotiable
Tracking number
can be offered to you within 24h
Supply Ability:
Mass in stock
FAQ
Question 1 , How do you pack the order ?
Discreet package , the packing suits you best would be choosen to cross customs safely
Question 2 , What is your shipping method ?
Shipping by express (FedEx,UPS,DHL,EMS,HKEMS,TNT), and cheapest by airmail
Question 3 , if my order seized by custom ,what do you do ?
Resending police if the tracking number do not update online or it sezied by custom
Questions 4 , What is your payment accept ?
Safe and fast payment :Western Union ,Money Gram ,T/T ,Bitcoin
Questions 5 , Will you supply tracking number ?
Yes ,we supply tracking number for following .In general ,once we supply the tracking number to you ,you can track the parcel information within 1-2 business days
Question 6 , How many days will it take to my country after I do the payment ?
In general ,fastest with 3-5 business , slowest 5-7 business days
Hot selling market
United State(USA) , United Kingdom(UK) , Australia , Canada , Spain , France , Germany , Russia , Brasil(Brazil) , Ukraine , South Africa , Norway , Poland , Netherlands(Holland) , Slovakia , Georgia , New Zealand , Sweden etc.
Â
Product name: Selumetinib
Other name: 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide; 6-(4-bromo-2-chlorophenylamino)-7-fluoro-N-(2-hydroxyethoxy)-3-methyl-3H-benzo[d]imidazole-5-carboxamide; Selumetinib; AZD6244; 5-[ (4-BROMO-2-CHLOROPHENYL)AMINO]-4-FLUORO-N-(2-HYDROXYETHOXY)-1-METHYL-1H-BENZIMIDAZOLE-6-CARBOXAMIDE;
MF:C17H15BrClFN4O3
MW:457.685
CAS:606143-52-6
Appearance and traits: white or light white solid
Density: 1.69
Storage conditions: Powder stores in -20oC directly, which is effective for a period of 2 years.
Customs Code: 2934999090
Package: 100g/foil bag
Smetatinib Description
Smetatinib, in previous studies, showed that sematantin also has the effect of treating metastatic biliary cancer.
The first-line treatment strategy for low-grade serous ovarian cancer is surgery followed by radiotherapy. However, this type of tumor grows slowly and responds poorly to traditional chemotherapy drugs. Because MEK gene mutations have been demonstrated in low-grade serous ovarian or peritoneal cancers, studies using MEK-1/2 protein kinases targeting mitogen-activated protein kinase (MAPK) pathway have been performed with seletinib. The study was performed on 52 patients with 100 mg of seletinib administered orally twice a day for 4 weeks, and 33% of patients received 12 or more cycles of treatment. Before the start of the study, 58% of patients had received 3 or more cycles of chemotherapy. Simetinib controlled disease in 81% of patients. In particular, 8 patients had complete or partial remission, and 34 had stable disease. The median progression-free survival was 11 months, and 63% of patients had a progression-free survival of more than 6 months. In addition, patients were well tolerated with simetinib and only 3 patients experienced grade 4 adverse events.
The clinical application of MEK inhibitors (mitogen activation inhibitors) is gradually being applied. It can be used first to treat chronic pain, inhibit cancer cell proliferation, treat non-small cell lung cancer, and MEK inhibitors can be combined with nilotinib to overcome them. Chronic myelogenous leukemia (CML) resistance. Recent treatment of metastatic biliary cancer and control of low-grade serous ovarian or peritoneal cancer. Therefore, the MEK inhibitor seletinib will become a new drug for treating cancer.
Factory and workshop
 Commerce Clause
Minimum Order Quantity:
100gram
Price:
Negotiable
Payment Terms:
Western Union, MoneyGram, T/T, Bank Transfer;Bitcoin
Packaging Details:
Discreet and Disguised packing
Delivery time:
Within 12 hours after receiving the payment
Leading time:
4~6 working days after confirming the payment
Delivery
By DHL, TNT, FedEx, HKEMS, UPS, etc.(Door to Door)bulk order can be negotiable
Tracking number
can be offered to you within 24h
Supply Ability:
Mass in stock
FAQ
Question 1 , How do you pack the order ?
Discreet package , the packing suits you best would be choosen to cross customs safely
Question 2 , What is your shipping method ?
Shipping by express (FedEx,UPS,DHL,EMS,HKEMS,TNT), and cheapest by airmail
Question 3 , if my order seized by custom ,what do you do ?
Resending police if the tracking number do not update online or it sezied by custom
Questions 4 , What is your payment accept ?
Safe and fast payment :Western Union ,Money Gram ,T/T ,Bitcoin
Questions 5 , Will you supply tracking number ?
Yes ,we supply tracking number for following .In general ,once we supply the tracking number to you ,you can track the parcel information within 1-2 business days
Question 6 , How many days will it take to my country after I do the payment ?
In general ,fastest with 3-5 business , slowest 5-7 business days
Hot selling market
United State(USA) , United Kingdom(UK) , Australia , Canada , Spain , France , Germany , Russia , Brasil(Brazil) , Ukraine , South Africa , Norway , Poland , Netherlands(Holland) , Slovakia , Georgia , New Zealand , Sweden etc.
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99% Selumetinib CAS 606143-52-6 for Treating Metastatic Biliary Cancer
Model NO.: 606143-52-6
Shipping Time: Within 24 Hours After Payment
Delivery: 3-5 Business Days
Customs Success Rate: >99%
Shipping Method: DHL, FedEx, TNT, Hkems, EMS Express
Supply Ability: Mess in Stock
Payment: T/T, Western Union, Money Gram, Bitcoin
MOQ: 10g
Trademark: Pharmcy
Transport Package: Customized
Specification: ISO9001
Origin: China
HS Code: 846321864
Model NO.: 606143-52-6
Shipping Time: Within 24 Hours After Payment
Delivery: 3-5 Business Days
Customs Success Rate: >99%
Shipping Method: DHL, FedEx, TNT, Hkems, EMS Express
Supply Ability: Mess in Stock
Payment: T/T, Western Union, Money Gram, Bitcoin
MOQ: 10g
Trademark: Pharmcy
Transport Package: Customized
Specification: ISO9001
Origin: China
HS Code: 846321864
99% Selumetinib CAS 606143-52-6 for  treating metastatic biliary cancer