According to recent results from researchers at Georgia State University, a class of organic compounds can effectively fight Ebola and other viral infections. The researchers found that this compound called benzoquinoline inhibits the ability of Ebola virus to replicate and proliferate in cell culture. The results were published in the most recent issue of Antiviral Research. The Ebola virus is a member of the filamentous virus, a membrane-enveloped single-stranded RNA virus that infects humans and causes severe symptoms. Between 2013 and 2016, a large-scale Ebola virus infection broke out in West Africa, which is also the largest-ever line of viral infections in the history. In this outbreak, 28,000 people were infected and 11,000 people died. There is currently no effective treatment or drug for Ebola virus infection, so we urgently need a new type of therapy. The current potential antiviral target is to kill the virus by blocking the synthesis of its RNA. In this study, the authors screened 200,000 small-molecule compounds and found that 56 compounds had a significant inhibitory effect (70%), while the corresponding cytotoxicity was less than 20%, and finally found 3 with In vitro antiviral effect of the compound structure. Later, the authors performed various types of virus treatment on human epithelial cells and HEK cells, and tested the antiviral effects of these drugs, among which benzoquinoline has a broad spectrum of antiviral activity. Based on this result, the authors hope to develop benzoquinoline-based anti-Ebola virus-infected drugs. Best hot selling men bath robe, waterproof dry robe, dry Change Robe, surf change robe, windproof cahnge robe, swim bath robe supplier.
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