Midea develops new compounds for the treatment of diabetes

A report published on the UK’s “Nature” website on the 4th said that American researchers have developed a novel compound that can be used for the treatment of diabetes. Compared with existing drugs, it can improve blood glucose levels but has no related side effects.

Researchers at the Scripps Research Institute in the United States reported that the new compound, SR1664, works by interfering with the function of certain proteins to help treat diabetes.

The researchers used SR1664 and the existing hypoglycemic agent Wendiya to treat experimental mice with diabetes. The results showed that both can improve the blood glucose level of the experimental rats, but Avandia has the side effects such as weight gain of the experimental rats, new Compounds have no associated side effects. The compound also does not have the side effects of hypoglycemic agents such as Avandia that affect bones.

Patrick Griffin, who led the study, said that the target of SR1664 is those known targets for the treatment of diabetes, but its unique mechanism of action is that it has both therapeutic functions and no side effects. Researchers will work hard to develop drugs for clinical treatment based on them.