Pharmaceutical Raw Materials Baclofen Powder

October 31, 2018

Model NO.: 99%
CAS: 1134-47-0
Trademark: TJ
Transport Package: Camouflage Package
Specification: White powder
Origin: China
HS Code: 3001200010
Model NO.: 99%
CAS: 1134-47-0
Trademark: TJ
Transport Package: Camouflage Package
Specification: White powder
Origin: China
HS Code: 3001200010

Quick Detail:
Product Name: Baclofen
Tag: gamma-aminobutyric acid, GABA, Kemstro,Lioresal,Liofen,Gablofen,Lyflex,Beklo,Baclosan
Synonym Kemstro,Lioresal,Liofen,Gablofen,Lyflex,Beklo,Baclosan
CAS 1134-47-0
MF C10H12ClNO2
MW 213.66
EINECS 214-486-9
Assay 99%
Quality Standards Enterprise Standard/Pharma Grade
Appearance White powder
Place of Origin China
Certification ISO9001, ISO14000, USP
Model Number 1134-47-0
MOQ: 1 g
Packaging Details 25kg/Drum, 1kg/bag
Delivery Time 5-7 days
Payment Terms T/T, Western union, Money gram

Description:
Baclofen is a γ-aminobutyric acid derivative. It is an antispasmodics class drugs acting on the central nervous system, the brain and spinal cord as a skeletal muscle relaxants and sedatives. It take antispasmodic effect by stimulating receptors to inhibit the release of excitatory amino acids such as glutamic acid, aspartic acid and thereby inhibiting the transfer of single and multi-synaptic reflex in central nervous system, brain and spinal cord.

Clinically it has already been used as racemic agent for treating Muscle spasticity since mid-1960s.Recent studies have also found that this product can significantly reduce the symptoms of gastroesophageal reflux and alleviating related symptoms. It can also alleviate the dystonia of children and treat the urination dysfunction caused by central spinal cord injury. In addition, the intrathecal injection therapy of the product in clinical application can further improve the clinical efficacy, and make it possible to adjust drugs dosage which stabilizes the treatment effect.

Application:
Baclofen powder also known as β-(4-chlorophenyl)-γ-aminobutyric acid (β-(4-chlorophenyl)-GABA), used as a skeletal muscle relaxant. It is primarily used to treat spasticity. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.

It is a GABA receptor agonist, specifically of the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. It is a derivative of γ-aminobutyric acid (GABA).

A beneficial property of baclofen is that tolerance to its muscle-related therapeutic benefits does not seem to occur to a significant degree - baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some people receiving intrathecal baclofen treatment.

Specifications:

Items Tested Specification Result
Characters A white, crystalline powder or colorless crystals. A white crystal.
Identification IR should comply with the Reference Standard spectrum.
UV should comply with the Reference Standard spectrum.
An orange-red precipitate is performed.		 IR complies with the Reference standard spectrum.
UV complies with the Reference standard spectrum.
An orange-red precipitate is performed.
Melting range 88 ~92 degree 89.8-90.2degree
Loss on Drying Not more than 1.0% 0.22%
Readily carbonizable Substances The resolution has no more color than Matching Fluid A. Conform
Residue on ignition Not more than 0.1% 0.02%
Heavy metals Not more than 0.001% Conform
Chloride Conform Conform
Assay (HPLC) 98.0%-102.0% 99.5%
Ordinary Impurities ≤1% Conform
Reaction Conform Conform
Conclusion Complies to USP31

Our adwantage:
1, High quality with competitive price:
    1) Standard: Enterprise Standard
    2) All Purity≥98%
    3) We are manufacturer and can provide high quality products with factory price.

2, Fast and safe delivery
    1) Parcel can be sent out within 24 hours after payment. Tracking number available
    2) Secure and discreet shipment. Various transportation methods for your choice.
    3) Customs pass rate ≥99%
    4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

3, We have clients throughout the world.
    1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
    2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
    3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

Pharmaceutical Raw Materials Baclofen Powder
 

 

Quick Detail:
Product Name: Baclofen
Tag: gamma-aminobutyric acid, GABA, Kemstro,Lioresal,Liofen,Gablofen,Lyflex,Beklo,Baclosan
Synonym Kemstro,Lioresal,Liofen,Gablofen,Lyflex,Beklo,Baclosan
CAS 1134-47-0
MF C10H12ClNO2
MW 213.66
EINECS 214-486-9
Assay 99%
Quality Standards Enterprise Standard/Pharma Grade
Appearance White powder
Place of Origin China
Certification ISO9001, ISO14000, USP
Model Number 1134-47-0
MOQ: 1 g
Packaging Details 25kg/Drum, 1kg/bag
Delivery Time 5-7 days
Payment Terms T/T, Western union, Money gram

Description:
Baclofen is a γ-aminobutyric acid derivative. It is an antispasmodics class drugs acting on the central nervous system, the brain and spinal cord as a skeletal muscle relaxants and sedatives. It take antispasmodic effect by stimulating receptors to inhibit the release of excitatory amino acids such as glutamic acid, aspartic acid and thereby inhibiting the transfer of single and multi-synaptic reflex in central nervous system, brain and spinal cord.

Clinically it has already been used as racemic agent for treating Muscle spasticity since mid-1960s.Recent studies have also found that this product can significantly reduce the symptoms of gastroesophageal reflux and alleviating related symptoms. It can also alleviate the dystonia of children and treat the urination dysfunction caused by central spinal cord injury. In addition, the intrathecal injection therapy of the product in clinical application can further improve the clinical efficacy, and make it possible to adjust drugs dosage which stabilizes the treatment effect.

Application:
Baclofen powder also known as β-(4-chlorophenyl)-γ-aminobutyric acid (β-(4-chlorophenyl)-GABA), used as a skeletal muscle relaxant. It is primarily used to treat spasticity. It is also used by compounding pharmacies in topical pain creams as a muscle relaxant.

It is a GABA receptor agonist, specifically of the GABAB receptors. Its beneficial effects in spasticity result from actions at spinal and supraspinal sites. It is a derivative of γ-aminobutyric acid (GABA).

A beneficial property of baclofen is that tolerance to its muscle-related therapeutic benefits does not seem to occur to a significant degree - baclofen retains its therapeutic anti-spasmodic effects even after many years of continued use. Newer studies, however, indicate that tolerance may develop in some people receiving intrathecal baclofen treatment.

Specifications:

Items Tested Specification Result
Characters A white, crystalline powder or colorless crystals. A white crystal.
Identification IR should comply with the Reference Standard spectrum.
UV should comply with the Reference Standard spectrum.
An orange-red precipitate is performed.		 IR complies with the Reference standard spectrum.
UV complies with the Reference standard spectrum.
An orange-red precipitate is performed.
Melting range 88 ~92 degree 89.8-90.2degree
Loss on Drying Not more than 1.0% 0.22%
Readily carbonizable Substances The resolution has no more color than Matching Fluid A. Conform
Residue on ignition Not more than 0.1% 0.02%
Heavy metals Not more than 0.001% Conform
Chloride Conform Conform
Assay (HPLC) 98.0%-102.0% 99.5%
Ordinary Impurities ≤1% Conform
Reaction Conform Conform
Conclusion Complies to USP31

Our adwantage:
1, High quality with competitive price:
    1) Standard: Enterprise Standard
    2) All Purity≥98%
    3) We are manufacturer and can provide high quality products with factory price.

2, Fast and safe delivery
    1) Parcel can be sent out within 24 hours after payment. Tracking number available
    2) Secure and discreet shipment. Various transportation methods for your choice.
    3) Customs pass rate ≥99%
    4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

3, We have clients throughout the world.
    1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
    2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
    3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.

Pharmaceutical Raw Materials Baclofen Powder
 

 

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