Release date: 2017-03-08 The team at the University of California, San Francisco has discovered the key to molecular aging in the blood and immune systems and is expected to address chronic diseases caused by aging, anemia, blood cancer, and various disease problems caused by infection. The study, published in the journal Nature, says that in addition to normal cellular waste disposal, autophagy has hematopoietic stem cells (hsc) for orderly maintenance, as well as the entire immune system that fights infections and treats pathogens. influences. The researchers found that autophagy inhibits hepatic stellate cells and allows the metabolically active hepatic stellate cells to return to rest and rest. This is a new discovery of autophagy in stem cell biology. Unactivated autophagy has a profound effect on the blood system, leading to imbalances in certain types of white blood cells. Autophagy defects also reduce the ability of hepatic stellate cells to regenerate. By conducting experiments in mice, the researchers found that 70% of hepatic stellate cells in aging mice do not undergo autophagy and generally exhibit dysfunctional properties. In addition, scientists have discovered many different tissue stem cells, all of which will decrease with age. “This discovery provides a new perspective on anti-aging, focusing on old hepatic stellate cells and slowing down the aging blood system. We hope to find a way to really improve the stem cells themselves and use this ability to help older people pass Stop the development of blood diseases and provide them with a better immune system to fight infections." Source: Noble Zhuhai Mingke Electronics Technology Co., Ltd , https://www.mingke-tech.com