Author: Zhang Meng Ran Release Date: 2018-12-10 British "Nature" magazine published a breakthrough medical achievement online on the 6th: the German team of scientists developed an improved method to achieve long-term work after the genetically modified pig heart transplanted into the body. This is the first method that can produce successful results repeatedly, and it represents a major step forward in the clinical development of human heart transplantation technology for pig hearts. Transplantation is the only long-term intervention available for patients with advanced heart failure. However, a viable organ supply cannot meet current clinical needs. Therefore, it has been proposed to use genetically modified pig hearts to help address this shortage and have conducted preclinical trials in the sputum model. However, the longest survival period for sputum transplants involving pigs was only 57 days. Now, Bruno Richard, a scientist at the University of Munich in Germany, and his colleagues have shown that longer survival can be achieved repeatedly. The research team used three consecutive groups of transplanted subjects (a total of 16 baboons) to improve the technique and successfully implemented long-term transplantation in the last group. The specific practice of the scientists is to allow the heart to be oxygenated by blood circulation (rather than static refrigeration) during the transplant process; and to prevent harmful enlargement of the transplanted organ by lowering the blood pressure of the sputum and using compounds known to control cell growth. The last group had a total of 5 ticks, 4 of which remained at least 90 days of health (experimental termination) and the longest remained for 195 days. Further trials are needed to improve the data, but this approach has shown tremendous progress, and the maturity of the study will largely alleviate the shortage of organ transplants. Xenotransplantation makes many people uncomfortable to hear, but in fact, if animal organs can be transplanted into humans and survive for a long time, although the recipient may rely on immunosuppressants to spend the rest of their lives, they can still be countless desperate patients. Hold up hope. In the entire medical community, it will also greatly alleviate the shortage of transplantable organs. In this process, pig organs are our best choice for xenotransplantation. Although cockroaches are very similar to us, the organs of pigs are biologically similar to us. At the same time, humans are already well aware of the DNA of pigs, and genetic modification is easier for scientists. Source: Technology Daily Black Garlic,Fermented Black Garlic,Black Garlic Puree,Natural Fermented Black Garlic Powder shandong changrong international trade co.,ltd. , https://www.cragriculture.com