People's Daily Tianjin May 23rd (Reporter Zhu Hong) On May 22nd, the Synthetic Biology Research Team led by Prof. Yuanying Jin of Tianjin University published three research papers in the same issue of the “Nature·Communications†journal and introduced precise control. Genome rearrangement technology and a series of research results. This achievement fills the technical gap in genomic structure variation, improves the production efficiency of cell factories, and accelerates the evolution of microorganisms and the discovery of biological knowledge. This is another major technological advance in the process of “designing life, recreating life, and reshaping life†following the artificial synthesis of yeast chromosomes to break the boundaries between non-living substances and life substances, and has opened up the rearrangement of genomes in synthetic biology research. This new research area. In the field of life sciences, genetic variation is the source of biological evolution, and there are challenges with artificially constructed techniques at the level of complex genomic structure variation. Tianjin University’s scientific research team is aiming at this problem and has developed a method that can precisely control the rearrangement of the genome. This makes the microorganism, which is the research object, produce geometrically-increasing genome mutations within a limited time, which drives its rapid evolution. They also pioneered a variety of methods for stabilizing the biological activity of the mutated yeast strains and as cell factories to produce β-carotene with high efficiency. Saccharomyces cerevisiae is a model eukaryotic unicellular organism in biological research. Prof. Yuan Yingjin said: “Chemically synthetic yeast can help humans understand more fundamental biological issues on the one hand, and can rapidly evolve through genomic rearrangement systems on the other hand, in medicine, energy, environment, agriculture, There are strains with potential for application in industries such as industry." People's Daily (May 24, 2018, 13th edition)
Feline Infectious Peritonitis (FIP), referred to as Feline Infectious Peritonitis (FIP), is a fatal abnormal immune response that occurs in cats. It is caused by the mutation of the feline coronavirus carried by cats. As a high-incidence and fatal disease of pet cats, the current incidence of feline abdominal transmission is about 10%.
The symptoms of cats are usually divided into two categories, namely wet FIP and dry FIP, of which wet FIP accounts for the majority of all cases. About 70%, manifested as abdominal pleural effusion, abnormal bulging; dry FIP cats have different symptoms, depending on the type of organ affected by the virus.
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