Chinese scientists use gene therapy to reverse the progress of diabetes research

Chinese researchers reported on April 4 that they used gene therapy technology to produce large amounts of omega-3 fatty acids in type I diabetic mice, successfully reversing the disease process. This brings new hope to the cure of patients suffering from type 1 diabetes. The study, led by professors of Guangdong University of Technology, Zhao Zijian and Li Fanghong, was published in the new issue of the American Journal of Clinical Examination.

Type I diabetes is an autoimmune disease that cannot be reversed once a patient is ill, will rely on insulin for life, and should monitor blood sugar regularly. At present, there is no drug or technology in the world to control autoimmunity and promote islet cell regeneration, in order to achieve the goal of reversing the autoimmune process and curing diabetes.

我国科学家利用基因疗法逆转糖尿病研究进程

The research team has learned from years of clinical research abroad: infants with a family history of type I diabetes who take long-term use of deep-sea fish oil after weaning can significantly reduce the risk of type 1 diabetes. However, if you want to reverse the autoimmune imbalance and the development of diabetes by supplementing fish oil, the dose required will greatly exceed the current clinically approved dose, which is difficult to achieve in reality. To this end, the researchers expressed a specific enzyme by gene therapy, which enabled the body to produce a large amount of omega-3 fatty acids EPA and DHA.

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