Metastasis is one of the most common causes of death in colorectal cancer. However, there has been no effective method for studying primary colorectal metastasis. Recently, researchers at the Massachusetts Institute of Technology (MIT) used CRISPR gene editing technology to generate colorectal tumors in mice. This tumor spreads to the liver and is very similar to human colorectal cancer. The results of this research can help scientists gain a deeper understanding of tumor progression and test new cancer therapies. The study was led by the Koch Institute for Integrative Cancer Research and published in the May 1 issue of Nature, Nature Biotechnology. â–² One of the authors of this study is Dr. Tyler Jacks of MIT Daniel (Source: MIT) Dr. Tyler Jacks, director of the Koch Cancer Institute, is also one of the authors of this article. “CRISPR technology has revolutionized many aspects of cancer research, including building disease mouse models faster and more accurately. It's a good example." Simulated human tumor For many years, cancer researchers have often used two methods to build cancer models. One is to culture cancer cell lines in the laboratory - immortalized human cancer cells. Scientists have discovered many cancer mechanisms in these two-dimensional cell lines, but they still have large limitations—not truly reflecting the complex internal environment of the tumor. Another widely used technique is genetically engineered mice that carry genetic mutations that are prone to cancer. However, breeding such mice can take several years, especially when more than one cancer-related mutation needs to be inserted. â–²CRISPR technology principle (Source: Cambridge University Press) Vinegar,White Rice Vinegar,White Vinegar,Millet Vinegar Chinese Seasoning (Shandong) Trading Co.,Ltd , https://www.zt-trading.com
