Propranolol can be used for the treatment of hyperthyroidism June 28, 2017 Source: China Pharmaceutical News Author: Zhu Hao this Propranolol is an adrenergic neuropeptide blocker that can be used to alleviate some of the clinical symptoms of hyperthyroidism. It has long been observed that many of the symptoms and signs of hyperthyroidism are similar to those of adrenergic hyperactivity, such as increased heart rate, high blood pressure, and agitation, as well as adrenaline and body tissue when suffering from hyperthyroidism. The sensitivity of norepinephrine is enhanced. This inspires people to try some drugs that block the function of the adrenergic nervous system to control certain symptoms of hyperthyroidism. After the 1950s, people began to use adjuvant treatments for hyperthyroidism with antihypertensive drugs such as reserpine and guanethidine, and found that these drugs can actually reduce the condition of patients with hyperthyroidism. Propranolol is an adrenergic neuropeptide blocker, although the mechanism of action with reserpine and guanethidine is different, but the results obtained are somewhat similar. Propranolol blocks beta receptors, slowing heart rate, impaired cardiac contractility and atrioventricular conduction, decreased cardiac output, and reduced myocardial oxygen consumption. Therefore, propranolol can alleviate the cardiovascular systemic activity of many adrenergic nerves in patients with hyperthyroidism. Generally, the symptoms of palpitations are obviously alleviated or eliminated 8 to 48 hours after administration. Symptoms such as agitation, nervousness or tremor often follow. It is getting better. The drug is also commonly used to treat thyroid crisis. After application, it can quickly reduce tachycardia, fever, restlessness and disorientation, and can also convert arrhythmia into sinus rhythm. The indications for propranolol in the treatment of hyperthyroidism are as follows: elderly hyperthyroidism, faster heart rate; hyperthyroidism with atrial fibrillation, tachycardia; in the late stage of antithyroid medication, symptom relief, basal metabolic rate returned to normal, However, if you have a heart rate, you can add this medicine or reserpine; thyroid crisis patients; adjuvant treatment of iodine-131. Because propranolol has the effect of inhibiting the heart and contracting bronchial smooth muscle, it is contraindicated in patients with atrioventricular block and bronchial asthma, and should be used with caution in heart failure. This medicine has no direct effect on thyroid function and can not reduce the basal metabolic rate when hyperthyroidism is increased, so it needs to be combined with other antithyroid drugs. Custom Procedure Pack Components Pack Components,Medical Pack Components,Procedure Pack Component,Custom Procedure Pack Components ShaoXing SurgeCare Medical Products Co., Ltd. , https://www.sxsurgecaremedical.com