American scientists use pluripotent stem cells to treat hair loss

Researchers at the Sanford Birmingham Medical Institute in the United States use induced pluripotent stem cells (iPSCs) to develop new hair. This study is the first to treat hair loss for people based on cells.

Release date: 2015-02-27

Researchers at the Sanford Birmingham Medical Institute in the United States use induced pluripotent stem cells (iPSCs) to develop new hair. This study is the first to treat hair loss for people based on cells. The findings were published online in the Public Library of Science.

According to statistics, in the United States alone, more than 40 million men and 21 million women suffer from hair loss. According to a recent report by the Physicist Organization Network, Dr. Alexei, associate professor of aging and regeneration development at the Sanford Birmingham Medical Institute, said: "We have developed a new cell that uses human induced pluripotent stem cells to trigger human hair growth. method."

He said: "This method significantly improves the existing method of transplanting a portion of the existing hair follicles of the head to the hair loss section. This method of stem cells provides an unlimited source of cells for hair loss, independent of the availability of existing hair follicles. limit."

The team induced human pluripotent stem cells to develop into dermal papilla cells, a unique group of cells that regulate hair follicle formation and growth cycle. Human dermal papilla cells rapidly lose their ability to induce hair follicle formation during cultivation because they are unable to obtain the necessary amount themselves, and are not suitable for hair transplantation.

Alexei said: "Because human hairy nipple cells are not easily expanded outside the body, they quickly lose the inductive properties of their hair. The method we developed is to promote the differentiation of human pluripotent stem cells into dermal papilla cells, and When transplanted into mice, it demonstrated its ability to induce hair growth."

Alexei said: "We will begin human testing in the next step, transplanting human dermal papilla cells derived from human pluripotent stem cells. We are now seeking partners to achieve this last step."

Source: China Science and Technology Network

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