Release date: 2015-09-08 By using replaceable laser, a new generation of desktop flow cytometer (eg ACEA biological company NOVOCYTE â„¢ flow cytometry) both excellent performance and customizable features, which gave birth to a cost-effective platform for cell analysis Description: Essen Bio (Hangzhou) Co., Ltd. is ACEA Biosciences Author: MATTHIAS SCHULZE, Coherent. The power of flow cytometry Flow cytometry is a laser-based technique designed for cell analysis (and sometimes for cell separation). The cells are first treated with a fluorescent antibody that binds to a particular cell type, and the prepared cells are then arranged in a single column through a focused laser beam. The detected fluorescent label can indicate the number and type of various cells in the sample. Flow cytometers are typically equipped with multiple lasers and can use many photodetectors with different wavelength channels or scattering angles. It is thus possible to simultaneously analyze a cell sample based on a plurality of parameters. Development of the desktop cytometer market Flow cytometry is a powerful research tool (eg for microbiology research) and it is also a widely used clinical practice in the field of rapid blood cell analysis (eg for monitoring CD4 cells in HIV-infected patients). tool. And, as new treatments (such as stem cell therapies) continue to be developed, new flow cytometry applications tend to become smaller and smaller between clinical and research measurements. This has led to the development of a new generation of benchtop instruments that are smaller and more economical than traditional floor-standing large instruments that can only be used for research. Customized performance is cost-effective performance Essen Biotech is a rising company in the desktop instrument market, and its development momentum is very fast. Rene Nunez, senior product manager at the company, believes that the combination of superior performance, functionality, speed and economics is critical to the desktop instrument market. He explained: "Almost every user of ours needs a high-performance instrument that is comparable to traditional large platforms in terms of sensitivity, data fidelity and productivity. But the investment cost of a large platform is high, and usually Lack of users in research Some features needed. Each application requires a unique set of features that provide different laser wavelengths and number of detection channels. Customers may need to have the appropriate configuration of the instrument for the most subtle inspections, automated sample processing, and the option to upgrade in the future. Flexibility and economy are key factors in this market. " Figure 1. Flow cytometry uses a focused laser to count fluorescently labeled cells. The signal is derived from a fluorescent label (fluorescent dye) that binds to the target protein and other cell surface markers. Figure 2. Essen Bio's desktop NovoCyte can be customized at the factory or configured on-site due to its modular design, including intelligent plug-and-play OBIS laser modules from coherent companies. Figure 3. The OBIS Smart Laser Module provides plug-and-play functionality and a uniform form factor covering a wide wavelength spectrum Intelligent plug and play laser module In response to this market demand, ACEA has introduced a new line of NovoCyte benchtop cytometers with a high level of internal modular design. "This is a very flexible platform, we can only provide the laser wavelengths that each customer specifically requires, and the option to change or upgrade the functionality by adding module components in the future, and can be implemented without returning to the factory," Nunez explained. It is well known that flow cytometry requires a high degree of precision, and it is difficult for lasers to calibrate and combine at such an accuracy level. However, we have adopted the OBIS intelligent laser module from Coherent, which perfectly overcomes this in the Novocyte series. A challenge. In particular, these plug-and-play independent intelligent modules have consistent mechanical registration and docking performance. Each OBIS module provides the same beam shape, size and orientation, making it easier to replace or add lasers. "" Suppliers need to be agile and a platform that can be modularized, customizable, and easily replaceable to better support the desktop cytometer market. Source: Bio Valley Knee Massage,Leg Knee Massager,Best Knee Massager,Leg And Knee Massager Shenzhen Jie Zhong Lian Investment Co., Ltd. , https://www.meizons.com
