5 applications for medical 3D printing in bioengineering: partial organ repair in the future

The development of medical health benefits from the help of technology, such as 3D printing, the custom repair of body organs can be more easily achieved. Bioengineers predict that it can be used to make real cellular materials in the future. Such technologies can be the basis for personalized biomedical devices, tissue engineered skin, cartilage and bones, and even working bladders. Recently published in the special issue of "Biotechnology Trends", researchers have sorted out and thought about the progress of 3D bioprinting and the ideas that may be realized in the next few years or even decades.

5 applications for medical 3D printing in bioengineering: partial organ repair in the future

This figure shows the process of printing high-throughput cells into microwells.

1. Custom chip organ

A 3D microengineering system that mimics the structure and function of human tissue – the “chip organ” – is a strong competitor in a cheap, efficient, and personalized medical competition. Lung, intestine, and pancreatic tissue can already be grown from human stem cells on the chip, allowing researchers to understand the physiological differences between these cells in different patients and to screen for drugs. The challenge of chip organ manufacturing is to rapidly expand the application of technology, while 3D printing can reduce the labor and expense required to build, direct, and meet the chip requirements.

"The intersection of 3D printed microfluidic manufacturing and bioprinting 3D organization is promising in single-step chip organ engineering and enables greater flexibility and throughput during the research process." From the University of Connecticut, working on 3D printing Savas Tasoglu (@SavasTasoglu), assistant professor of research and development for new applications in microfluidics and chip organs, said, "In future research, more advanced 3D bioprinters that print a range of viscous materials will be used in printing and manufacturing micro The fluid platform and the complex organization of the internal modeling of the device. This kind of closed integration system will greatly simplify the manufacture of the chip organ model and make the design of the chip organ iteratively faster."

5 applications for medical 3D printing in bioengineering: partial organ repair in the future

3D printing of biological cells in a microfluidic device

3D printing technology continues to be successful in microfluidic device manufacturing and bioprinting applications, and with the rapid innovation in these two areas, 3D printing will likely become a tool for chip organ engineering in the next few years. Currently, the availability of biocompatible printing materials limits the structural size of microfluidic channels and bioprinted tissue. However, with the rapid improvement in 3D printing resolution, even low-cost consumer-grade 3D printers are likely to solve this problem in the near future.

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