Release date: 2017-05-08 For the first time in history, scientists have identified the cause behind eczema, which can help us overcome this chronic disease. Recall that in 2006, researchers found a link between the lack of certain skin proteins and the risk of eczema. Now, based on these results, scientists have taken us closer to curing eczema. Eczema is a common skin condition affecting 20% ​​of children and 3 percent of adults worldwide. Although there are many plasters and lotions on the market to alleviate the symptoms of eczema, we still have not found a way to cure it. Over the past decade, scientists have known that eczema is associated with the loss of silk fibroin in the skin. This protein helps individuals shape their skin cells and plays an important role in the defense of our skin. If a person's genetic mutation makes him unable to produce filaggrin, he will develop skin diseases such as eczema and ichthyosis vulgaris (the skin cells will not fall off, but are stacked in a fish scale). However, before this, the researchers were not sure how to develop eczema when people lacked silk fibroin. Scientists from the University of Newcastle, England, and GlaxoSmithKline, tracked the molecular pathways that led to this skin disease. Nick Reynolds, a principal researcher at Newcastle University, said: "We found that the missing silk fibroin is enough to alter the key proteins and pathways that trigger eczema." To study these mechanisms, the team used a three-dimensional revitalization model created by the laboratory. They changed the top layer of this laboratory skin and let it lose the silk polyprotein. They found that this loss is enough to trigger a series of molecular changes in important management mechanisms in the skin. This affects cell structure, defense functions, and even cell inflammation and the way to cope with stress. The team pointed out: "It is worth noting that we first discovered that a total of 17 proteins have changed significantly after the lack of filaggrin in the revitalization model." The team then verified their initial findings by analyzing real skin samples. After comparing the skin conditions of eczema patients and healthy participants, they found that some proteins in eczema had the same changes. Although this is just one part of the mystery of eczema, once scientists know what's going on in the skin of the silk polyprotein, they can find the right medicine. Nina Goad, from the British Association of Dermatologists, said in a statement: "This type of research enables scientists to develop drugs that cure eczema, not just the symptoms." If you have eczema, this is really good news. The study was published in the Journal of Allergy and Clinical Immunology. Source: Omelette Net Insulin Syringes Needle,Disable Syringe,Monoject Syringe,10 Ml Syringe FOSHAN PHARMA CO., LTD. , https://www.foshanmedicine.com