[Dry goods] 6 technical experts talk about future medical technology

Li Xiang: Family application of molecular diagnosis

Cayudi Bio CEO Li Xiang introduces the market situation of molecular diagnostic products

In 2000, there was a human genome project, which was the power of all countries to complete a person's genome test, using a generation of sequencing, which cost $3 billion. Today, 15 years later, the human genome has been completed for a thousand dollars through second-generation sequencing technology. More people can benefit from this technology.

In 2015, our National Health and Family Planning Commission forced the introduction of the application of nucleic acid diagnostics in blood stations throughout the country. All major infectious diseases, including secondary diseases, hepatitis B and hepatitis C, must pass molecular diagnosis, not only to diagnose, but also to diagnose Can shorten the window period. In other words, it is necessary to wait for humans to produce antibodies for retesting, but it can be detected at the beginning of infection, which is the application of major infectious diseases.

At present, there are only 409 PCR laboratories in China, and only 200 second-generation sequencers. This technology is not popular. why? Molecular biology technology and semiconductor electronics technology originated in the 1950s, and the speed of development is far from comparable.

Nowadays, electronic technology has deeply affected people's lives, but molecular biology technology needs not only electrons, but also our biochemical reactions, that is, it has many biological reactions. There is also optics, as well as weak learning. This series of interdisciplinary subjects, making an instrument, even if it is small, but it will also be a very complicated, not a very simple instrument, which is why today's molecular diagnosis The development is still a process that has not yet been decentralized.

Diagnosing the company's entire annual revenue is only 58.8 billion US dollars, while pharmaceutical companies are 1 trillion US dollars, which is a very disparate proportion. What does it mean? Everyone is sick and may not go to the hospital. Only when they are very sick, they go to the hospital. The cost of this medicine is very heavy. This problem is solved by precision medicine .

For example, the use of tumor fluid biopsy to monitor the salivation of cancer, if you can screen it out early, you may be able to eliminate the tumor without surgery. There are also individualized medications, and different people should use different medicines. This is the core point of precision medicine . In other words, you don't have to try the medicine for the doctor. This medicine is customized for you, and it doesn't cost money or be misdiagnosed.

The virus will mutate. Once it is mutated to a more serious form, it will have a major impact on your body, including the entire infectious disease and public safety. If you can separate between severe and non-severe, the treatment of critical periods will be Very good diagnostic tool.

Huang Xiaomin: How to manage diabetes intelligently and accurately

Huang Xiaomin, CEO of Kailian Medical, introduced the challenges of diabetes management

According to the FDA survey, thousands of traffic accidents in the United States each year are associated with hypoglycemia.

The most important thing in diabetes management is to achieve a balance between high blood sugar and low blood sugar, which is true diabetes management.

As the most important test method for diabetes management, it is only 15% of the blood glucose monitoring in China. There are very few patients who perform tests on a daily basis, or more than four times a day, for four reasons:

1 Pain of blood collection 2 High frequency of blood collection 3 Timing of blood collection 4 Accuracy of blood glucose meter.

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